Anti-EMSY antibody (STJA0008085)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C11orf30
General Information
| Short Description | Rabbit polyclonal anti-BRCA2-interacting transcriptional repressor EMSY for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EMSY |
| Gene ID | 56946 |
| Uniprot ID | EMSY_HUMAN |
| Immunogen | Synthesized peptide derived from human C11orf30 |
| Specificity | This antibody detects endogenous levels of C11orf30 at Human, Mouse |
Additional Info
| Function | Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. Mediates ligand-dependent transcriptional activation by nuclear hormone receptors. |
| Protein Name | Brca2-Interacting Transcriptional Repressor Emsy |
| Database Links | |
| Cellular Localisation | NucleusLocalizes To Dna Damage Markers In Irradiated CellsSuggesting That It Participates In Dna Repair Process |
| Alternative Antibody Names | Anti-Brca2-Interacting Transcriptional Repressor Emsy antibodyAnti-EMSY antibodyAnti-C11orf30 antibodyAnti-GL002 antibody |
Information sourced from Uniprot.org