Anti-ELP2 antibody (300-600) (STJ118302)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ELP2 (300-600) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELP2 |
| Gene ID | 55250 |
| Uniprot ID | ELP2_HUMAN |
| Immunogen Region | 300-600 |
| Immunogen Sequence | QNTVNPREWTPEIVISGHFD GVQDLVWDPEGEFIITVGTD QTTRLFAPWKRKDQSQVTWH EIARPQIHGYDLKCLAMINR FQFVSGADEKVLRVFSAPRN FVENFCAITGQSLNHVLCNQ DSDLPEGATVPALGLSNKAV FQGDIASQPSDEEELLTSTG FEYQQVAFQPSILTEPPTED HLLQNTLWPEVQKLYGHGYE IFCVTCNSSKTLLASACKAA KKEHAAIILWNTTSWKQVQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human ELP2 (NP_001229808.1). |
Additional Info
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. |
| Protein Name | Elongator Complex Protein 2Elp2Shinc-2Stat3-Interacting Protein 1Stip1 |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Elongator Complex Protein 2 antibodyAnti-Elp2 antibodyAnti-Shinc-2 antibodyAnti-Stat3-Interacting Protein 1 antibodyAnti-Stip1 antibodyAnti-ELP2 antibodyAnti-STATIP1 antibody |
Information sourced from Uniprot.org