| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ELP2 |
| Gene ID: | 55250 |
| Uniprot ID: | ELP2_HUMAN |
| Immunogen Region: | 300-600 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human ELP2 (NP_001229808.1). |
| Immunogen Sequence: | QNTVNPREWTPEIVISGHFD GVQDLVWDPEGEFIITVGTD QTTRLFAPWKRKDQSQVTWH EIARPQIHGYDLKCLAMINR FQFVSGADEKVLRVFSAPRN FVENFCAITGQSLNHVLCNQ DSDLPEGATVPALGLSNKAV FQGDIASQPSDEEELLTSTG FEYQQVAFQPSILTEPPTED HLLQNTLWPEVQKLYGHGYE IFCVTCNSSKTLLASACKAA KKEHAAIILWNTTSWKQVQ |
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. |
| Protein Name | Elongator Complex Protein 2Elp2Shinc-2Stat3-Interacting Protein 1Stip1 |
| Database Links | Reactome: R-HSA-3214847 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Elongator Complex Protein 2 antibodyAnti-Elp2 antibodyAnti-Shinc-2 antibodyAnti-Stat3-Interacting Protein 1 antibodyAnti-Stip1 antibodyAnti-ELP2 antibodyAnti-STATIP1 antibody |
Information sourced from Uniprot.org