Anti-ELOVL6 antibody (50-150) (STJ11104179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Elongation Of Very Long Chain Fatty Acids Protein 6 (50-150) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELOVL6 |
| Gene ID | 79071 |
| Uniprot ID | ELOV6_HUMAN |
| Immunogen Region | 50-150 |
| Immunogen Sequence | LMNKRAKFELRKPLVLWSLT LAVFSIFGALRTGAYMVYIL MTKGLKQSVCDQGFYNGPVS KFWAYAFVLSKAPELGDTIF IILRKQKLIFLHWYHHITVL L |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ELOVL6 (NP_076995.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | N-Glycosylated. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 63-Keto Acyl-Coa Synthase Elovl6Elovl Fatty Acid Elongase 6Elovl Fa Elongase 6Elongation Of Very Long Chain Fatty Acids Protein 6Fatty Acid Elongase 2Helo2Fatty Acyl-Coa ElongaseLong-Chain Fatty-Acyl ElongaseVery Long Chain 3-Ketoacyl-Coa Synthase 6Very Long Chain 3-Oxoacyl-Coa Synthase 6 |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 6 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl6 antibodyAnti-Elovl Fatty Acid Elongase 6 antibodyAnti-Elovl Fa Elongase 6 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 6 antibodyAnti-Fatty Acid Elongase 2 antibodyAnti-Helo2 antibodyAnti-Fatty Acyl-Coa Elongase antibodyAnti-Long-Chain Fatty-Acyl Elongase antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 6 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 6 antibodyAnti-ELOVL6 antibodyAnti-FACE antibodyAnti-LCE antibody |
Information sourced from Uniprot.org