| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Elongation Of Very Long Chain Fatty Acids Protein 6 (50-150) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ELOVL6 |
| Gene ID: |
79071 |
| Uniprot ID: |
ELOV6_HUMAN |
| Immunogen Region: |
50-150 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ELOVL6 (NP_076995.1). |
| Immunogen Sequence: |
LMNKRAKFELRKPLVLWSLT LAVFSIFGALRTGAYMVYIL MTKGLKQSVCDQGFYNGPVS KFWAYAFVLSKAPELGDTIF IILRKQKLIFLHWYHHITVL L |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | N-Glycosylated. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Elongation Of Very Long Chain Fatty Acids Protein 63-Keto Acyl-Coa Synthase Elovl6Elovl Fatty Acid Elongase 6Elovl Fa Elongase 6Fatty Acid Elongase 2Helo2Fatty Acyl-Coa ElongaseLong-Chain Fatty-Acyl ElongaseVery Long Chain 3-Ketoacyl-Coa Synthase 6Very Long Chain 3-Oxoacyl-Coa Synthase 6 |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Elongation Of Very Long Chain Fatty Acids Protein 6 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl6 antibodyAnti-Elovl Fatty Acid Elongase 6 antibodyAnti-Elovl Fa Elongase 6 antibodyAnti-Fatty Acid Elongase 2 antibodyAnti-Helo2 antibodyAnti-Fatty Acyl-Coa Elongase antibodyAnti-Long-Chain Fatty-Acyl Elongase antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 6 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 6 antibodyAnti-ELOVL6 antibodyAnti-FACE antibodyAnti-LCE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
