| Short Description : | Rabbit monoclonal eIF2A (450-550) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S0MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EIF2A |
| Gene ID: | 83939 |
| Uniprot ID: | EIF2A_HUMAN |
| Immunogen Region: | 450-550 |
| Immunogen Sequence: | ALRNKPITNSKLHEEEPPQN MKPQSGNDKPLSKTALKNQR KHEAKKAAKQEARSDKSPDL APTPAPQSTPRNTVSQSISG DPEIDKKIKNLKKKLKAIEQ L |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 450-550 of human eIF2A (Q9BY44). |
| Tissue Specificity | Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta. |
| Function | Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. |
| Protein Name | Eukaryotic Translation Initiation Factor 2aEif-2a65 Kda Eukaryotic Translation Initiation Factor 2a Cleaved Into - Eukaryotic Translation Initiation Factor 2a - N-Terminally Processed |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Eukaryotic Translation Initiation Factor 2a antibodyAnti-Eif-2a antibodyAnti-65 Kda Eukaryotic Translation Initiation Factor 2a Cleaved Into - Eukaryotic Translation Initiation Factor 2a - N-Terminally Processed antibodyAnti-EIF2A antibodyAnti-CDA02 antibodyAnti-MSTP004 antibodyAnti-MSTP089 antibody |
Information sourced from Uniprot.org
