Anti-EHD4 antibody (362-541) (STJ115713)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EHD4 (362-541) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EHD4 |
| Gene ID | 30844 |
| Uniprot ID | EHD4_HUMAN |
| Immunogen Region | 362-541 |
| Immunogen Sequence | MQEQLENYDFTKFHSLKPKL IEAVDNMLSNKISPLMNLIS QEETSTPTQLVQGGAFDGTT EGPFNQGYGEGAKEGADEEE WVVAKDKPVYDELFYTLSPI NGKISGVNAKKEMVTSKLPN SVLGKIWKLADCDCDGMLDE EEFALAKHLIKIKLDGYELP SSLPPHLVPPSHRKSLPKAD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_644670.1). |
Additional Info
| Tissue Specificity | Highly expressed in pancreas and heart. |
| Function | ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport. During sprouting angiogenesis, in complex with PACSIN2 and MICALL1, forms recycling endosome-like tubular structure at asymmetric adherens junctions to control CDH5 trafficking. |
| Protein Name | Eh Domain-Containing Protein 4Hepatocellular Carcinoma-Associated Protein 10/11Past Homolog 4 |
| Database Links | |
| Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinCytoplasmic SideRecycling Endosome MembraneCell MembraneCell JunctionAdherens Junction |
| Alternative Antibody Names | Anti-Eh Domain-Containing Protein 4 antibodyAnti-Hepatocellular Carcinoma-Associated Protein 10/11 antibodyAnti-Past Homolog 4 antibodyAnti-EHD4 antibodyAnti-HCA10 antibodyAnti-HCA11 antibodyAnti-PAST4 antibodyAnti-FKSG7 antibody |
Information sourced from Uniprot.org