| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Pikachurin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EGFLAM |
| Gene ID: |
133584 |
| Uniprot ID: |
EGFLA_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Pikachurin at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human Pikachurin |
| Function | Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. |
| Protein Name | PikachurinAgrin-Like ProteinEgf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixSynaptic CleftPresynaptic Active ZoneDetected In The Synaptic Cleft Of The Ribbon Synapse Around The Postsynaptic Terminals Of Bipolar CellsColocalizes With BsnCtbp2 And Dag1 In Photoreceptor Synaptic Terminals |
| Alternative Antibody Names | Anti-Pikachurin antibodyAnti-Agrin-Like Protein antibodyAnti-Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein antibodyAnti-EGFLAM antibodyAnti-AGRINL antibodyAnti-AGRNL antibodyAnti-PIKA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
