Anti-EGFLAM antibody (STJA0008241)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Pikachurin
General Information
| Short Description | Rabbit polyclonal anti-Pikachurin for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EGFLAM |
| Gene ID | 133584 |
| Uniprot ID | EGFLA_HUMAN |
| Immunogen | Synthesized peptide derived from human Pikachurin |
| Specificity | This antibody detects endogenous levels of Pikachurin at Human, Mouse, Rat |
Additional Info
| Function | Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. |
| Protein Name | PikachurinAgrin-Like ProteinEgf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixSynaptic CleftPresynaptic Active ZoneDetected In The Synaptic Cleft Of The Ribbon Synapse Around The Postsynaptic Terminals Of Bipolar CellsColocalizes With BsnCtbp2 And Dag1 In Photoreceptor Synaptic Terminals |
| Alternative Antibody Names | Anti-Pikachurin antibodyAnti-Agrin-Like Protein antibodyAnti-Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein antibodyAnti-EGFLAM antibodyAnti-AGRINL antibodyAnti-AGRNL antibodyAnti-PIKA antibody |
Information sourced from Uniprot.org