Anti-EFEMP1 antibody (18-493 aa) [R01-7C7] (STJA0012357)

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STJA0012357-100
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Short Description :Rabbit monoclonal anti-EFEMP1 (18-493 aa) for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/IP
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R01-7C7
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.3 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IP 1:20
Formulation:50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:EFEMP1
Gene ID:2202
Uniprot ID:FBLN3_HUMAN
Immunogen:Recombinant protein of human EFEMP1/Fibulin-3
Immunogen Region:18-493 aa
Tissue Specificity In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.
Function Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Protein Name Egf-Containing Fibulin-Like Extracellular Matrix Protein 1
Extracellular Protein S1-5
Fibrillin-Like Protein
Fibulin-3
Fibl-3
Database Links Reactome: R-HSA-2129379
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Localizes To The Lamina Propria Underneath The Olfactory Epithelium
Alternative Antibody Names Anti-Egf-Containing Fibulin-Like Extracellular Matrix Protein 1 antibody
Anti-Extracellular Protein S1-5 antibody
Anti-Fibrillin-Like Protein antibody
Anti-Fibulin-3 antibody
Anti-Fibl-3 antibody
Anti-EFEMP1 antibody
Anti-FBLN3 antibody
Anti-FBNL antibody

Information sourced from Uniprot.org