| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IP |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-EFEMP1 (18-493 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
R01-7C7 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: |
Affinity Purified |
| Concentration: |
0.3 mg/ml |
| Dilution Range: |
WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: |
EFEMP1 |
| Gene ID: |
2202 |
| Uniprot ID: |
FBLN3_HUMAN |
| Immunogen Region: |
18-493 aa |
| Immunogen: |
Recombinant protein of human EFEMP1/Fibulin-3 |
| Tissue Specificity | In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina. |
| Function | Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
| Protein Name | Egf-Containing Fibulin-Like Extracellular Matrix Protein 1Extracellular Protein S1-5Fibrillin-Like ProteinFibulin-3Fibl-3 |
| Database Links | Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalizes To The Lamina Propria Underneath The Olfactory Epithelium |
| Alternative Antibody Names | Anti-Egf-Containing Fibulin-Like Extracellular Matrix Protein 1 antibodyAnti-Extracellular Protein S1-5 antibodyAnti-Fibrillin-Like Protein antibodyAnti-Fibulin-3 antibodyAnti-Fibl-3 antibodyAnti-EFEMP1 antibodyAnti-FBLN3 antibodyAnti-FBNL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
