Anti-Thioredoxin 2 antibody [R01-7C7] (STJA0034927)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Thioredoxin 2
General Information
| Short Description | Rabbit monoclonal anti-Thioredoxin 2 for use in WB, IHC-F, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-7C7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TXN2 |
| Gene ID | 25828 |
| Uniprot ID | THIOM_HUMAN |
| Immunogen | A synthetic peptide of human Thioredoxin 2 |
Additional Info
| Tissue Specificity | Widely expressed in adult (at protein level) and fetal tissues. |
| Function | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability Is involved in various redox reactions including the reduction of protein disulfide bonds, through the reversible oxidation of its active center dithiol to a disulfide. |
| Protein Name | Thioredoxin - MitochondrialMtrxMt-TrxThioredoxin-2 |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-3299685 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Thioredoxin - Mitochondrial antibodyAnti-Mtrx antibodyAnti-Mt-Trx antibodyAnti-Thioredoxin-2 antibodyAnti-TXN2 antibodyAnti-TRX2 antibody |
Information sourced from Uniprot.org