Anti-EDNRB antibody (31-80 aa) (STJ98617)

Name: Anti-EDNRB antibody (31-80 aa) (STJ98617)
SKU: STJ98617
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from ETBR at the amino acid range 31-80

STJ98617

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Short Description	Rabbit polyclonal anti-Endothelin receptor type B (31-80 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC/IF/ELISA
Host	Rabbit
Reactivity	Human/Rat/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	IHC-P 100-300 WB 1:500-2000 ELISA 1:10000-20000 IF 1:50-200
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	EDNRB
Gene ID	1910
Uniprot ID	EDNRB_HUMAN
Immunogen	Synthesized peptide derived from ETBR at the amino acid range 31-80
Immunogen Region	31-80 aa
Specificity	ETBR Polyclonal Antibody detects endogenous levels of ETBR

Post Translational Modifications	Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405.
Function	Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Protein Name	Endothelin Receptor Type B Et-B Et-Br Endothelin Receptor Non-Selective Type
Database Links	Reactome: R-HSA-375276 Reactome: R-HSA-416476 Reactome: R-HSA-9856649
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Internalized After Activation By Endothelins
Alternative Antibody Names	Anti-Endothelin Receptor Type B antibody Anti-Et-B antibody Anti-Et-Br antibody Anti-Endothelin Receptor Non-Selective Type antibody Anti-EDNRB antibody Anti-ETRB antibody

Information sourced from Uniprot.org