Anti-DYX1C1/EKN1 antibody (N-Term) (STJ70926)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DYX1C1/EKN1 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 48+40kDa bands observed in Human Brain (Cerebral Cortex and Frontal Cortex) lysates (calculated MW of 48.5kDa according to NP_570722.2 and of 44.0kDa according to NP_001028731.1 |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DNAAF4 |
| Gene ID | 161582 |
| Uniprot ID | DAAF4_HUMAN |
| Accession Number | NP_570722.2; NP_001028731.1; NP_001028732.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | PLQVSDYSWQQTKT |
| Specificity | This antibody is expected to recognise three reported isoforms (NP_570722.2, NP_001028731.1 and NP_001028732.1). |
Additional Info
| Function | Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. |
| Protein Name | Dynein Axonemal Assembly Factor 4Dyslexia Susceptibility 1 Candidate Gene 1 Protein |
| Cellular Localisation | NucleusCytoplasmDynein Axonemal ParticleCell ProjectionNeuron Projection |
| Alternative Antibody Names | Anti-Dynein Axonemal Assembly Factor 4 antibodyAnti-Dyslexia Susceptibility 1 Candidate Gene 1 Protein antibodyAnti-DNAAF4 antibodyAnti-DYX1C1 antibodyAnti-EKN1 antibody |
Information sourced from Uniprot.org