Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human/Dog |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-DYX1C1/EKN1 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000. WB: Approx 48+40kDa bands observed in Human Brain (Cerebral Cortex and Frontal Cortex) lysates (calculated MW of 48.5kDa according to NP_570722.2 and of 44.0kDa according to NP_001028731.1 |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | DNAAF4 |
Gene ID: | 161582 |
Uniprot ID: | DAAF4_HUMAN |
Immunogen Region: | N-Term |
Accession Number: | NP_570722.2; NP_001028731.1; NP_001028732.1 |
Specificity: | This antibody is expected to recognise three reported isoforms (NP_570722.2, NP_001028731.1 and NP_001028732.1). |
Immunogen Sequence: | PLQVSDYSWQQTKT |
Function | Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. |
Protein Name | Dynein Axonemal Assembly Factor 4 Dyslexia Susceptibility 1 Candidate Gene 1 Protein |
Cellular Localisation | Nucleus Cytoplasm Dynein Axonemal Particle Cell Projection Neuron Projection |
Alternative Antibody Names | Anti-Dynein Axonemal Assembly Factor 4 antibody Anti-Dyslexia Susceptibility 1 Candidate Gene 1 Protein antibody Anti-DNAAF4 antibody Anti-DYX1C1 antibody Anti-EKN1 antibody |
Information sourced from Uniprot.org