Anti-DYM antibody (30-80 aa) (STJ195657)

SKU:
STJ195657
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Dymeclin (30-80 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:DYM
Gene ID:54808
Uniprot ID:DYM_HUMAN
Immunogen:Synthesized peptide derived from the human DYM at the amino acid range 30-80
Immunogen Region:30-80 aa
Specificity:This antibody detects endogenous levels of DYM at Human/Mouse/Rat
Post Translational Modifications Myristoylated in vitro.myristoylation is not essential for protein targeting to Golgi compartment.
Function Necessary for correct organization of Golgi apparatus. Involved in bone development.
Protein Name Dymeclin
Dyggve-Melchior-Clausen Syndrome Protein
Database Links
Cellular Localisation Cytoplasm
Golgi Apparatus
Membrane
Lipid-Anchor
Sequence Analysis Programs Clearly Predict 1 Transmembrane Region
However
Pubmed:18996921 Shows That It Is Not A Stably Anchored Transmembrane Protein But It Weakly Associates With The Golgi Apparatus And Shuttles Between The Golgi And The Cytosol
Alternative Antibody Names Anti-Dymeclin antibody
Anti-Dyggve-Melchior-Clausen Syndrome Protein antibody
Anti-DYM antibody

Information sourced from Uniprot.org