• Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-DYM antibody (30-80 aa) (STJ195657)

SKU:
STJ195657

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dymeclin (30-80 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DYM
Gene ID: 54808
Uniprot ID: DYM_HUMAN
Immunogen Region: 30-80 aa
Specificity: This antibody detects endogenous levels of DYM at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human DYM at the amino acid range 30-80
Post Translational Modifications Myristoylated in vitro.myristoylation is not essential for protein targeting to Golgi compartment.
Function Necessary for correct organization of Golgi apparatus. Involved in bone development.
Protein Name Dymeclin
Dyggve-Melchior-Clausen Syndrome Protein
Cellular Localisation Cytoplasm
Golgi Apparatus
Membrane
Lipid-Anchor
Sequence Analysis Programs Clearly Predict 1 Transmembrane Region
However
Pubmed:18996921 Shows That It Is Not A Stably Anchored Transmembrane Protein But It Weakly Associates With The Golgi Apparatus And Shuttles Between The Golgi And The Cytosol
Alternative Antibody Names Anti-Dymeclin antibody
Anti-Dyggve-Melchior-Clausen Syndrome Protein antibody
Anti-DYM antibody

Information sourced from Uniprot.org

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