Anti-DUSP8/HVH5 antibody (N-Term) (STJ70123)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DUSP8/HVH5 (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 55-58kDa band observed in Human (Cerebellum) , Mouse and Rat Brain lysates (calculated MW of 65.8kDa according to Human NP_004411.2, 68.8kDa according to Mouse NP_032774.1 and 66 |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DUSP8 |
| Gene ID | 1850 |
| Uniprot ID | DUS8_HUMAN |
| Accession Number | NP_004411.2 |
| Immunogen Region | N-Term |
| Immunogen Sequence | AGDRLPRKVMDAK |
| Specificity | This antibody is also expected to recognise the hypothetical human protein similar to dual specificity phosphatase 8 (XM_114902) , which is virtually identical. |
Additional Info
| Function | Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues. |
| Protein Name | Dual Specificity Protein Phosphatase 8Dual Specificity Protein Phosphatase Hvh-5 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 8 antibodyAnti-Dual Specificity Protein Phosphatase Hvh-5 antibodyAnti-DUSP8 antibodyAnti-C11orf81 antibodyAnti-VH5 antibody |
Information sourced from Uniprot.org