| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DUSP15 |
| Gene ID: | 128853 |
| Uniprot ID: | DUS15_HUMAN |
| Immunogen Region: | 10-90 |
| Immunogen Sequence: | PGLYLGNFIDAKDLDQLGRN KITHIISIHESPQPLLQDIT YLRIPVADTPEVPIKKHFKE CINFIHCCRLNGGNCLVHCF A |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-90 of human DUSP15 (NP_542178.2). |
| Tissue Specificity | Highly expressed in testis. Expressed in brain.up-regulated in patients with multiple sclerosis gray matter lesions. |
| Function | May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6. Isoform 3: May play a role in the regulation of oligodendrocyte differentiation. May play a role in the regulation of myelin formation. Involved in the regulation of Erk1/2 phosphorylation in Schwann cells.the signaling may be linked to the regulation of myelination. |
| Protein Name | Dual Specificity Protein Phosphatase 15Vh1-Related Member YVaccinia Virus Vh1-Related Dual-Specific Protein Phosphatase Y |
| Database Links | |
| Cellular Localisation | CytoplasmIsoform 3: Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 15 antibodyAnti-Vh1-Related Member Y antibodyAnti-Vaccinia Virus Vh1-Related Dual-Specific Protein Phosphatase Y antibodyAnti-DUSP15 antibodyAnti-C20orf57 antibodyAnti-VHY antibody |
Information sourced from Uniprot.org
