| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DUSP10/MKP5 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000. WB: Approx 53kDa band seen in Human Liver lysate. Recommended for use at 0.5-2µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DUSP10 |
| Gene ID: | 11221 |
| Uniprot ID: | DUS10_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_009138.1; NP_653329.1; NP_653330.1 |
| Specificity: | This antibody is expected to recognise both reported Human isofoms. The variants NP_653329.1 and NP_653330.1 represent identical protein. |
| Immunogen Sequence: | CRILTPKLMGVETVV |
| Function | Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38. |
| Protein Name | Dual Specificity Protein Phosphatase 10 Mitogen-Activated Protein Kinase Phosphatase 5 Map Kinase Phosphatase 5 Mkp-5 |
| Database Links | Reactome: R-HSA-112409 Reactome: R-HSA-5675221 Reactome: R-HSA-9652817 |
| Cellular Localisation | Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 10 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 5 antibody Anti-Map Kinase Phosphatase 5 antibody Anti-Mkp-5 antibody Anti-DUSP10 antibody Anti-MKP5 antibody |
Information sourced from Uniprot.org