Anti-DUSP10/MKP5 antibody (C-Term) (STJ70125)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DUSP10/MKP5 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 53kDa band seen in Human Liver lysate. Recommended for use at 0.5-2µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DUSP10 |
| Gene ID | 11221 |
| Uniprot ID | DUS10_HUMAN |
| Accession Number | NP_009138.1; NP_653329.1; NP_653330.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | CRILTPKLMGVETVV |
| Specificity | This antibody is expected to recognise both reported Human isofoms. The variants NP_653329.1 and NP_653330.1 represent identical protein. |
Additional Info
| Function | Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38. |
| Protein Name | Dual Specificity Protein Phosphatase 10Mitogen-Activated Protein Kinase Phosphatase 5Map Kinase Phosphatase 5Mkp-5 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 10 antibodyAnti-Mitogen-Activated Protein Kinase Phosphatase 5 antibodyAnti-Map Kinase Phosphatase 5 antibodyAnti-Mkp-5 antibodyAnti-DUSP10 antibodyAnti-MKP5 antibody |
Information sourced from Uniprot.org