Anti-DUSP1 antibody (C-Term) (STJ70069)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DUSP1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Dog/Cow/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 40kDa band observed in lysates of HeLa (calculated MW of 39.3kDa according to NP_004408.1). Recommended concentration: 1-3µg/ml. Primary incubation was 1 hour. Preliminary testi |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DUSP1 |
| Gene ID | 1843 |
| Uniprot ID | DUS1_HUMAN |
| Accession Number | NP_004408.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | SYLQSPITTSPSC |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. |
| Protein Name | Dual Specificity Protein Phosphatase 1Dual Specificity Protein Phosphatase Hvh1Mitogen-Activated Protein Kinase Phosphatase 1Map Kinase Phosphatase 1Mkp-1Protein-Tyrosine Phosphatase Cl100 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 1 antibodyAnti-Dual Specificity Protein Phosphatase Hvh1 antibodyAnti-Mitogen-Activated Protein Kinase Phosphatase 1 antibodyAnti-Map Kinase Phosphatase 1 antibodyAnti-Mkp-1 antibodyAnti-Protein-Tyrosine Phosphatase Cl100 antibodyAnti-DUSP1 antibodyAnti-CL100 antibodyAnti-MKP1 antibodyAnti-PTPN10 antibodyAnti-VH1 antibody |
Information sourced from Uniprot.org