Anti-DRD2 antibody {FITC} (STJ500713)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein.
STJ500713-100
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General Information

Short DescriptionRabbit polyclonal antibody anti-DRD2 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
ApplicationsCM/ELISA/ICC/IF/IHC/IP/WB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationFITC
Concentration0.55ยตg/ยตl
PurificationAffinity Purified
Dilution RangeWB: 1:1, 000-1:1, 5000
ELISA: 1:50, 000
IP: 1:200
IHC: 1:200
ICC: 1:200
IF: 1:200
FormulationContains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage InstructionStore at-20ยฐC for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolDRD2
Gene ID1813
Uniprot IDDRD2_HUMAN
ImmunogenSynthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein.

Additional Info

Tissue Specificity Isoform 1: Expressed in the anterior pituitary gland. Isoform 2: Expressed in the anterior pituitary gland.
Post Translational Modifications Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Protein Name D(2 Dopamine Receptor
Dopamine D2 Receptor
Database Links Reactome: R-HSA-390651
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Antibody Names Anti-D(2 Dopamine Receptor antibody
Anti-Dopamine D2 Receptor antibody
Anti-DRD2 antibody

Information sourced from Uniprot.org

Citations

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