Anti-DRD2 antibody {FITC} (STJ500713)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationFITC
IsotypeIgG
ImmunogenSynthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-DRD2 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | CM/ELISA/ICC/IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | FITC |
| Concentration | 0.55ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:1, 000-1:1, 5000ELISA: 1:50, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | DRD2 |
| Gene ID | 1813 |
| Uniprot ID | DRD2_HUMAN |
| Immunogen | Synthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein. |
Additional Info
| Tissue Specificity | Isoform 1: Expressed in the anterior pituitary gland. Isoform 2: Expressed in the anterior pituitary gland. |
| Post Translational Modifications | Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8. |
| Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. |
| Protein Name | D(2 Dopamine ReceptorDopamine D2 Receptor |
| Database Links | Reactome: R-HSA-390651 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus Membrane |
| Alternative Antibody Names | Anti-D(2 Dopamine Receptor antibodyAnti-Dopamine D2 Receptor antibodyAnti-DRD2 antibody |
Information sourced from Uniprot.org