Anti-DRD2 antibody (13-443) (STJ114796)

Name: Anti-DRD2 antibody (13-443) (STJ114796)
SKU: STJ114796
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ114796

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Short Description	Rabbit polyclonal DRD2 (13-443) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:100-1:500 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DRD2
Gene ID	1813
Uniprot ID	DRD2_HUMAN
Immunogen Region	13-443
Immunogen Sequence	MDPLNLSWYDDDLERQNWSR PFNGSDGKADRPHYNYYATL LTLLIAVIVFGNVLVCMAVS REKALQTTTNYLIVSLAVAD LLVATLVMPWVVYLEVVGEW
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DRD2 (NP_000786.1).

Tissue Specificity	Isoform 1: Expressed in the anterior pituitary gland. Isoform 2: Expressed in the anterior pituitary gland.
Post Translational Modifications	Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.
Function	Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Protein Name	D(2 Dopamine Receptor Dopamine D2 Receptor
Database Links	Reactome: R-HSA-390651
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Golgi Apparatus Membrane
Alternative Antibody Names	Anti-D(2 Dopamine Receptor antibody Anti-Dopamine D2 Receptor antibody Anti-DRD2 antibody

Information sourced from Uniprot.org