Anti-DR1 antibody (STJA0008252)

SKU:
STJA0008252

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein Dr1 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DR1
Gene ID: 1810
Uniprot ID: NC2B_HUMAN
Specificity: This antibody detects endogenous levels of DR1 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human DR1
Function The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Protein Name Protein Dr1
Down-Regulator Of Transcription 1
Negative Cofactor 2-Beta
Nc2-Beta
Tata-Binding Protein-Associated Phosphoprotein
Database Links Reactome: R-HSA-3214847
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Protein Dr1 antibody
Anti-Down-Regulator Of Transcription 1 antibody
Anti-Negative Cofactor 2-Beta antibody
Anti-Nc2-Beta antibody
Anti-Tata-Binding Protein-Associated Phosphoprotein antibody
Anti-DR1 antibody

Information sourced from Uniprot.org

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