| Short Description : | Rabbit monoclonal anti-DPEP3 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Purified |
| Dilution Range: | IHC 1:100-1:200 |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | DPEP3 |
| Gene ID: | 64180 |
| Uniprot ID: | DPEP3_HUMAN |
| Immunogen: | A synthesized peptide derived from human DPEP3 |
| Function | Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance. |
| Protein Name | Dipeptidase 3 |
| Database Links | |
| Cellular Localisation | MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Dipeptidase 3 antibodyAnti-DPEP3 antibodyAnti-UNQ834 antibodyAnti-PRO1772 antibody |
Information sourced from Uniprot.org