Anti-DPEP3 antibody (STJA0037905)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human DPEP3
General Information
| Short Description | Rabbit monoclonal anti-DPEP3 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DPEP3 |
| Gene ID | 64180 |
| Uniprot ID | DPEP3_HUMAN |
| Immunogen | A synthesized peptide derived from human DPEP3 |
Additional Info
| Function | Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance. |
| Protein Name | Dipeptidase 3 |
| Database Links | |
| Cellular Localisation | MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Dipeptidase 3 antibodyAnti-DPEP3 antibodyAnti-UNQ834 antibodyAnti-PRO1772 antibody |
Information sourced from Uniprot.org