| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dedicator of cytokinesis protein 4 (533-583 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DOCK4 |
| Gene ID: |
9732 |
| Uniprot ID: |
DOCK4_HUMAN |
| Immunogen Region: |
533-583 aa |
| Specificity: |
This antibody detects endogenous levels of DOCK4 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human DOCK4 at the amino acid range 533-583 |
| Function | Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration. Isoform 2: Has a higher guanine nucleotide exchange factor activity compared to other isoforms. |
| Protein Name | Dedicator Of Cytokinesis Protein 4 |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-983231 |
| Cellular Localisation | Cell MembraneCell ProjectionCytoplasmCytosolColocalizes With Epha2Rhog And Cttn/Cortactin At The Tip Of Protrusions In Migrating Cells |
| Alternative Antibody Names | Anti-Dedicator Of Cytokinesis Protein 4 antibodyAnti-DOCK4 antibodyAnti-KIAA0716 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
