Anti-DOC2A antibody (233-246) (STJ72667)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DOC2A (233-246) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx 50kDa band in Human, Mouse and Rat Brain lysates after 0.3 ยตg/ml antibody staining. Please note that currently we cannot find an explanation in t |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DOC2A |
| Gene ID | 8448 |
| Uniprot ID | DOC2A_HUMAN |
| Accession Number | NP_003577.2 |
| Immunogen Region | 233-246 |
| Immunogen Sequence | SCYLKELEQAEQGQ |
Additional Info
| Function | Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. |
| Protein Name | Double C2-Like Domain-Containing Protein AlphaDoc2Doc2-Alpha |
| Cellular Localisation | LysosomeCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePeripheral Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Double C2-Like Domain-Containing Protein Alpha antibodyAnti-Doc2 antibodyAnti-Doc2-Alpha antibodyAnti-DOC2A antibody |
Information sourced from Uniprot.org