Anti-DMRT2 antibody (C-Term) (STJ73076)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DMRT2 (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.IHC: In paraffin embedded Human Kidney shows nuclear staining primarily in the DCT. Recommended concentration, 2-4µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DMRT2 |
| Gene ID | 10655 |
| Uniprot ID | DMRT2_HUMAN |
| Accession Number | NP_006548.1; NP_870987.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | KRPSSAITRVSQ |
| Specificity | This antibody is expected to recognize isoform 2 only (NP_870987.2). Reported variants NP_001124337.1 and NP_006548.1 represent identical protein |
Additional Info
| Function | Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome. |
| Protein Name | Doublesex- And Mab-3-Related Transcription Factor 2Doublesex-Like 2 ProteinDsxl-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Doublesex- And Mab-3-Related Transcription Factor 2 antibodyAnti-Doublesex-Like 2 Protein antibodyAnti-Dsxl-2 antibodyAnti-DMRT2 antibodyAnti-DSXL2 antibody |
Information sourced from Uniprot.org