• Western blot analysis of various lysates using DLL4 Rabbit polyclonal antibody (STJ114809) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-DLL4 antibody (317-530) (STJ114809)

SKU:
STJ114809

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DLL4 (317-530) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DLL4
Gene ID: 54567
Uniprot ID: DLL4_HUMAN
Immunogen Region: 317-530
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 317-530 of human DLL4 (NP_061947.1).
Immunogen Sequence: TGVDCELELSECDSNPCRNG GSCKDQEDGYHCLCPPGYYG LHCEHSTLSCADSPCFNGGS CRERNQGANYACECPPNFTG SNCEKKVDRCTSNPCANGGQ CLNRGPSRMCRCRPGFTGTY CELHVSDCARNPCAHGGTCH DLENGLMCTCPAGFSGRRCE VRTSIDACASSPCFNRATCY TDLSTDTFVCNCPYGFVGSR CEFPVGLPPSFPWV
Tissue Specificity Expressed in vascular endothelium.
Function Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis.negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
Protein Name Delta-Like Protein 4
Drosophila Delta Homolog 4
Delta4
Database Links Reactome: R-HSA-2122948
Reactome: R-HSA-2644606
Reactome: R-HSA-2660826
Reactome: R-HSA-2691232
Reactome: R-HSA-2894862
Reactome: R-HSA-2979096
Reactome: R-HSA-9013507
Reactome: R-HSA-9013700
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Delta-Like Protein 4 antibody
Anti-Drosophila Delta Homolog 4 antibody
Anti-Delta4 antibody
Anti-DLL4 antibody
Anti-UNQ1895 antibody
Anti-PRO4341 antibody

Information sourced from Uniprot.org

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