Anti-DISP1 antibody (1325-1524) (STJ117145)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DISP1 (1325-1524) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DISP1 |
| Gene ID | 84976 |
| Uniprot ID | DISP1_HUMAN |
| Immunogen Region | 1325-1524 |
| Immunogen Sequence | FVHPITHIHHCPCLQGRVKP AGMQNSLPRNFFLHPVQHIQ AQEKIGKTNVHSLQRSIEEH LPKMAEPSSFVCRSTGSLLK TCCDPENKQRELCKNRDVSN LESSGGTENKAGGKVELSLS QTDASVNSEHFNQNEPKVLF NHLMGEAGCRSCPNNSQSCG RIVRVKCNSVDCQMPNMEAN VPAVLTHSELSGESLLIKTL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1325-1524 of human DISP1 (NP_116279.2). |
Additional Info
| Function | Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion. |
| Protein Name | Protein Dispatched Homolog 1 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Dispatched Homolog 1 antibodyAnti-DISP1 antibodyAnti-DISPA antibody |
Information sourced from Uniprot.org