| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DISP1 |
| Gene ID: | 84976 |
| Uniprot ID: | DISP1_HUMAN |
| Immunogen Region: | 1325-1524 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1325-1524 of human DISP1 (NP_116279.2). |
| Immunogen Sequence: | FVHPITHIHHCPCLQGRVKP AGMQNSLPRNFFLHPVQHIQ AQEKIGKTNVHSLQRSIEEH LPKMAEPSSFVCRSTGSLLK TCCDPENKQRELCKNRDVSN LESSGGTENKAGGKVELSLS QTDASVNSEHFNQNEPKVLF NHLMGEAGCRSCPNNSQSCG RIVRVKCNSVDCQMPNMEAN VPAVLTHSELSGESLLIKTL |
| Function | Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal. Synergizes with SCUBE2 to cause an increase in SHH secretion. |
| Protein Name | Protein Dispatched Homolog 1 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein Dispatched Homolog 1 antibodyAnti-DISP1 antibodyAnti-DISPA antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and MRP4/ABCC4 knockdown (KD) 293T cells, using [KD Validated] MRP4/ABCC4 Rabbit monoclonal antibody (STJ11104887) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/177531/369344/STJ11104887_1__18269.1713134835.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MRP4/ABCC4 knockdown (KD) 293T cells, using [KD Validated] MRP4/ABCC4 Rabbit monoclonal antibody (STJ11104887) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
