• Immunofluorescence analysis of NIH/3T3 cells using DiMethyl-DNMT3A-K44 antibody (STJ118453) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using DiMethyl-DNMT3A-K44 antibody (STJ118453) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of HeLa cells using DiMethyl-DNMT3A-K44 antibody (STJ118453) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of U2OS cells using DiMethyl-DNMT3A-K44 antibody (STJ118453) at dilution of 1:100. Blue: DAPI for nuclear staining.

Anti-DiMethyl-DNMT3A-K44 antibody (STJ118453)

SKU:
STJ118453
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Host: Rabbit
Applications: IF
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal primary antibody against DNMT3A K44me2.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: IF: 1:50-1:200
Uniprot ID: DNM3A_MOUSE
Gene ID: 13435
Gene Symbol: Dnmt3a
Immunogen: A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1).
Background CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Database Links Reactome: R-MMU-212300

Information sourced from uniprot.org

6 months standard