• Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1, primary Antibody was diluted at 1:200 (4°C overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval (>98°C, 20min). 3, Secondary antibody was diluted at 1:200

Anti-DIAPH2 antibody (STJ193155)

SKU:
STJ193155

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein diaphanous homolog 2 is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
WB 1:500-2000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DIAPH2
Gene ID: 1730
Uniprot ID: DIAP2_HUMAN
Specificity: This antibody detects endogenous levels of human DIAP2
Immunogen: Synthesized peptide derived from the human DIAP2
Function Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
Protein Name Protein Diaphanous Homolog 2
Diaphanous-Related Formin-2
Drf2
Database Links Reactome: R-HSA-5663220
Reactome: R-HSA-9013405 O60879-3
Reactome: R-HSA-9035034
Cellular Localisation Isoform 3: Cytoplasm
Cytosol
Early Endosome
Isoform 3 Is Cytosolic But When Coexpressed With Rhod
The 2 Proteins Colocalize To Early Endosomes
Alternative Antibody Names Anti-Protein Diaphanous Homolog 2 antibody
Anti-Diaphanous-Related Formin-2 antibody
Anti-Drf2 antibody
Anti-DIAPH2 antibody
Anti-DIA antibody

Information sourced from Uniprot.org

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