Anti-DIAPH2 antibody (STJ193155)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DIAP2
General Information
| Short Description | Rabbit polyclonal anti-Protein diaphanous homolog 2 for use in IHC, IF and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200WB 1:500-2000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DIAPH2 |
| Gene ID | 1730 |
| Uniprot ID | DIAP2_HUMAN |
| Immunogen | Synthesized peptide derived from the human DIAP2 |
| Specificity | This antibody detects endogenous levels of human DIAP2 |
Additional Info
| Function | Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. |
| Protein Name | Protein Diaphanous Homolog 2Diaphanous-Related Formin-2Drf2 |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013405 O60879-3Reactome: R-HSA-9035034 |
| Cellular Localisation | Isoform 3: CytoplasmCytosolEarly EndosomeIsoform 3 Is Cytosolic But When Coexpressed With RhodThe 2 Proteins Colocalize To Early Endosomes |
| Alternative Antibody Names | Anti-Protein Diaphanous Homolog 2 antibodyAnti-Diaphanous-Related Formin-2 antibodyAnti-Drf2 antibodyAnti-DIAPH2 antibodyAnti-DIA antibody |
Information sourced from Uniprot.org