Anti-DHFR2 antibody (31-81 aa) (STJ193860)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human DYRL1 at the amino acid range 31-81
General Information
| Short Description | Rabbit polyclonal anti-Dihydrofolate reductase 2, mitochondrial (31-81 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHFR2 |
| Gene ID | 200895 |
| Uniprot ID | DYR2_HUMAN |
| Immunogen | Synthesized peptide derived from the human DYRL1 at the amino acid range 31-81 |
| Immunogen Region | 31-81 aa |
| Specificity | This antibody detects endogenous levels of DYRL1 at Human |
Additional Info
| Function | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. |
| Protein Name | Dihydrofolate Reductase 2 - MitochondrialDihydrofolate Reductase - MitochondrialDihydrofolate Reductase-Like Protein 1 |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | MitochondrionMitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Dihydrofolate Reductase 2 - Mitochondrial antibodyAnti-Dihydrofolate Reductase - Mitochondrial antibodyAnti-Dihydrofolate Reductase-Like Protein 1 antibodyAnti-DHFR2 antibodyAnti-DHFRL1 antibodyAnti-DHFRP4 antibody |
Information sourced from Uniprot.org