| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Dihydrofolate reductase 2, mitochondrial (31-81 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DHFR2 |
| Gene ID: |
200895 |
| Uniprot ID: |
DYR2_HUMAN |
| Immunogen Region: |
31-81 aa |
| Specificity: |
This antibody detects endogenous levels of DYRL1 at Human |
| Immunogen: |
Synthesized peptide derived from the human DYRL1 at the amino acid range 31-81 |
| Function | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. |
| Protein Name | Dihydrofolate Reductase 2 - MitochondrialDihydrofolate Reductase - MitochondrialDihydrofolate Reductase-Like Protein 1 |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | MitochondrionMitochondrion MatrixMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Dihydrofolate Reductase 2 - Mitochondrial antibodyAnti-Dihydrofolate Reductase - Mitochondrial antibodyAnti-Dihydrofolate Reductase-Like Protein 1 antibodyAnti-DHFR2 antibodyAnti-DHFRL1 antibodyAnti-DHFRP4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
