| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Deoxyguanosine kinase, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DGUOK |
| Gene ID: | 1716 |
| Uniprot ID: | DGUOK_HUMAN |
| Specificity: | This antibody detects endogenous levels of dGK at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human dGK |
| Function | Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents. |
| Protein Name | Deoxyguanosine Kinase - MitochondrialDeoxyadenosine Kinase - Mitochondrial |
| Database Links | Reactome: R-HSA-74217 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Deoxyguanosine Kinase - Mitochondrial antibodyAnti-Deoxyadenosine Kinase - Mitochondrial antibodyAnti-DGUOK antibodyAnti-DGK antibody |
Information sourced from Uniprot.org