Anti-DGUOK antibody (STJA0008552)

SKU:
STJA0008552

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Deoxyguanosine kinase, mitochondrial is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DGUOK
Gene ID: 1716
Uniprot ID: DGUOK_HUMAN
Specificity: This antibody detects endogenous levels of dGK at Human, Mouse
Immunogen: Synthesized peptide derived from human dGK
Function Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
Protein Name Deoxyguanosine Kinase - Mitochondrial
Deoxyadenosine Kinase - Mitochondrial
Database Links Reactome: R-HSA-74217
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Deoxyguanosine Kinase - Mitochondrial antibody
Anti-Deoxyadenosine Kinase - Mitochondrial antibody
Anti-DGUOK antibody
Anti-DGK antibody

Information sourced from Uniprot.org

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