Anti-Desmoglein 1/DSG1 antibody (Internal) (STJ72005)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Desmoglein 1/DSG1 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments in lysates of cell lines A431, HeLa, K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1µg/ml).IHC: In paraffin em |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DSG1 |
| Gene ID | 1828 |
| Uniprot ID | DSG1_HUMAN |
| Accession Number | NP_001933.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | YTTSDTLKPSVHVHD |
Additional Info
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-1Cadherin Family Member 4Desmosomal Glycoprotein 1Dg1DgiPemphigus Foliaceus Antigen |
| Database Links | Reactome: R-HSA-351906Reactome: R-HSA-6798695Reactome: R-HSA-6805567Reactome: R-HSA-6809371Reactome: R-HSA-9696264Reactome: R-HSA-9696270 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosomeCytoplasmNucleus |
| Alternative Antibody Names | Anti-Desmoglein-1 antibodyAnti-Cadherin Family Member 4 antibodyAnti-Desmosomal Glycoprotein 1 antibodyAnti-Dg1 antibodyAnti-Dgi antibodyAnti-Pemphigus Foliaceus Antigen antibodyAnti-DSG1 antibodyAnti-CDHF4 antibody |
Information sourced from Uniprot.org