Anti-Dennd4c antibody (Internal) (STJ72467)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Dennd4c (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 210kDa band observed in Mouse Spleen lysates (calculated MW of 211kDa according to NP_908976.1). Recommended concentration: 0.5-2ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Accession Number | NP_908976.1; NP_001074483.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | RFKPQSPYRAYKDRS |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_908976.1; NP_001074483.1). |
Additional Info
| Function | Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin. |
| Protein Name | Denn Domain-Containing Protein 4c |
| Database Links | Reactome: R-MMU-8876198 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneCell MembraneCytoplasmCytosolAssociates With Slc2a4/Glut4 Storage Vesicles |
| Alternative Antibody Names | Anti-Denn Domain-Containing Protein 4c antibodyAnti-Dennd4c antibody |
Information sourced from Uniprot.org