| Short Description : | Rabbit polyclonal anti-Beta-defensin 1 (1-50 aa) for use in IHC and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IHC-P 1:50-200ELISA-Pep 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DEFB1 |
| Gene ID: | 1672 |
| Uniprot ID: | DEFB1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human Beta-defensin 1 at the amino acid range 1-50 |
| Immunogen Region: | 1-50 aa |
| Specificity: | This antibody detects endogenous levels of human Beta-defensin 1 |
| Function | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Protein Name | Beta-Defensin 1Bd-1Hbd-1Defensin - Beta 1 |
| Database Links | Reactome: R-HSA-1461957Reactome: R-HSA-1461973 |
| Cellular Localisation | SecretedMembraneAssociates With Tumor Cell Membrane-Derived Microvesicles |
| Alternative Antibody Names | Anti-Beta-Defensin 1 antibodyAnti-Bd-1 antibodyAnti-Hbd-1 antibodyAnti-Defensin - Beta 1 antibodyAnti-DEFB1 antibodyAnti-BD1 antibodyAnti-HBD1 antibody |
Information sourced from Uniprot.org
