Anti-DEFB1 antibody (1-50 aa) (STJ196527)

Name: Anti-DEFB1 antibody (1-50 aa) (STJ196527)
SKU: STJ196527
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthesized peptide derived from the human Beta-defensin 1 at the amino acid range 1-50

STJ196527

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Short Description	Rabbit polyclonal anti-Beta-defensin 1 (1-50 aa) for use in IHC and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IHC/ELISA
Host	Rabbit
Reactivity	Human/Rat/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	1 mg/mL
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range	IHC-P 1:50-200 ELISA-Pep 1:5000-20000
Formulation	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DEFB1
Gene ID	1672
Uniprot ID	DEFB1_HUMAN
Immunogen	Synthesized peptide derived from the human Beta-defensin 1 at the amino acid range 1-50
Immunogen Region	1-50 aa
Specificity	This antibody detects endogenous levels of human Beta-defensin 1

Function	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
Protein Name	Beta-Defensin 1 Bd-1 Hbd-1 Defensin - Beta 1
Database Links	Reactome: R-HSA-1461957 Reactome: R-HSA-1461973
Cellular Localisation	Secreted Membrane Associates With Tumor Cell Membrane-Derived Microvesicles
Alternative Antibody Names	Anti-Beta-Defensin 1 antibody Anti-Bd-1 antibody Anti-Hbd-1 antibody Anti-Defensin - Beta 1 antibody Anti-DEFB1 antibody Anti-BD1 antibody Anti-HBD1 antibody

Information sourced from Uniprot.org