| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DDAH2 (1-285) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:100IF/ICC 1:10-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DDAH2 |
| Gene ID: |
23564 |
| Uniprot ID: |
DDAH2_HUMAN |
| Immunogen Region: |
1-285 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human DDAH2 (NP_039268.1). |
| Immunogen Sequence: |
MGTPGEGLGRCSHALIRGVP ESLASGEGAGAGLPALDLAK AQREHGVLGGKLRQRLGLQL LELPPEESLPLGPLLGDTAV IQGDTALITRPWSPARRPEV DGVRKALQDLGLRIVEIGDE NATLDGTDVLFTGREFFVGL SKWTNHRGAEIVADTFRDFA VSTVPVSGPSHLRGLCGMGG PRTVVAGSSDAAQKAVRAMA VLTDHPYASLTLPDDAAADC LFLRPGLPGVPPFLLHRGG |
| Tissue Specificity | Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain. |
| Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
| Protein Name | N(G -N(G-Dimethylarginine Dimethylaminohydrolase 2Ddah-2Dimethylarginine Dimethylaminohydrolase 2DdahiiDimethylargininase-2Protein G6aS-Phase Protein |
| Database Links | Reactome: R-HSA-203615 |
| Cellular Localisation | CytoplasmMitochondrionTranslocates From Cytosol To Mitochondrion Upon Il-1beta Stimulation In Chondrocytes |
| Alternative Antibody Names | Anti-N(G -N(G-Dimethylarginine Dimethylaminohydrolase 2 antibodyAnti-Ddah-2 antibodyAnti-Dimethylarginine Dimethylaminohydrolase 2 antibodyAnti-Ddahii antibodyAnti-Dimethylargininase-2 antibodyAnti-Protein G6a antibodyAnti-S-Phase Protein antibodyAnti-DDAH2 antibodyAnti-DDAH antibodyAnti-G6A antibodyAnti-NG30 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
