Anti-DDAH1 antibody (1-285) (STJ112333)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DDAH1 (1-285) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DDAH1 |
| Gene ID | 23576 |
| Uniprot ID | DDAH1_HUMAN |
| Immunogen Region | 1-285 |
| Immunogen Sequence | MAGLGHPAAFGRATHAVVRA LPESLGQHALRSAKGEEVDV ARAERQHQLYVGVLGSKLGL QVVELPADESLPDCVFVEDV AVVCEETALITRPGAPSRRK EVDMMKEALEKLQLNIVEMK DENATLDGGDVLFTGREFFV GLSKRTNQRGAEILADTFKD YAVSTVPVADGLHLKSFCSM AGPNLIAIGSSESAQKALKI MQQMSDHRYDKLTVPDDIAA NCIYLNIPNKGHVLLHRTP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human DDAH1 (NP_036269.1). |
Additional Info
| Tissue Specificity | Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. |
| Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
| Protein Name | N(G -N(G-Dimethylarginine Dimethylaminohydrolase 1Ddah-1Dimethylarginine Dimethylaminohydrolase 1DdahiDimethylargininase-1 |
| Database Links | Reactome: R-HSA-203615 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-N(G -N(G-Dimethylarginine Dimethylaminohydrolase 1 antibodyAnti-Ddah-1 antibodyAnti-Dimethylarginine Dimethylaminohydrolase 1 antibodyAnti-Ddahi antibodyAnti-Dimethylargininase-1 antibodyAnti-DDAH1 antibodyAnti-DDAH antibody |
Information sourced from Uniprot.org