| Short Description : | Rabbit polyclonal DDAH1 (1-285) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DDAH1 |
| Gene ID: | 23576 |
| Uniprot ID: | DDAH1_HUMAN |
| Immunogen Region: | 1-285 |
| Immunogen Sequence: | MAGLGHPAAFGRATHAVVRA LPESLGQHALRSAKGEEVDV ARAERQHQLYVGVLGSKLGL QVVELPADESLPDCVFVEDV AVVCEETALITRPGAPSRRK EVDMMKEALEKLQLNIVEMK DENATLDGGDVLFTGREFFV GLSKRTNQRGAEILADTFKD YAVSTVPVADGLHLKSFCSM AGPNLIAIGSSESAQKALKI MQQMSDHRYDKLTVPDDIAA NCIYLNIPNKGHVLLHRTP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human DDAH1 (NP_036269.1). |
| Tissue Specificity | Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. |
| Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
| Protein Name | N(G -N(G-Dimethylarginine Dimethylaminohydrolase 1Ddah-1Dimethylarginine Dimethylaminohydrolase 1DdahiDimethylargininase-1 |
| Database Links | Reactome: R-HSA-203615 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-N(G -N(G-Dimethylarginine Dimethylaminohydrolase 1 antibodyAnti-Ddah-1 antibodyAnti-Dimethylarginine Dimethylaminohydrolase 1 antibodyAnti-Ddahi antibodyAnti-Dimethylargininase-1 antibodyAnti-DDAH1 antibodyAnti-DDAH antibody |
Information sourced from Uniprot.org
