Anti-DBP antibody (1-325) (STJ117465)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DBP (1-325) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DBP |
| Gene ID | 1628 |
| Uniprot ID | DBP_HUMAN |
| Immunogen Region | 1-325 |
| Immunogen Sequence | MARPVSDRTPAPLLLGGPAG TPPGGGALLGLRSLLQGTSK PKEPASCLLKEKERKAALPA ATTPGPGLETAGPADAPAGA VVGGGSPRGRPGPVPAPGLL APLLWERTLPFGDVEYVDLD AFLLEHGLPPSPPPPGGPSP EPSPARTPAPSPGPGSCGSA SPRSSPGHAPARAALGTASG HRAGLTSRDTPSPVDPDTVE VLMTFEPDPADLALSSIPGH ETFDPRRHRFSEEELKPQP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human DBP (NP_001343.2). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity. |
| Function | This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. |
| Protein Name | D Site-Binding ProteinAlbumin D Box-Binding ProteinAlbumin D-Element-Binding ProteinTax-Responsive Enhancer Element-Binding Protein 302Taxreb302 |
| Database Links | Reactome: R-HSA-1368108 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-D Site-Binding Protein antibodyAnti-Albumin D Box-Binding Protein antibodyAnti-Albumin D-Element-Binding Protein antibodyAnti-Tax-Responsive Enhancer Element-Binding Protein 302 antibodyAnti-Taxreb302 antibodyAnti-DBP antibody |
Information sourced from Uniprot.org