Anti-DBF4 antibody (10-59 aa) (STJ92660)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DBF4 at the amino acid range 10-59
General Information
| Short Description | Rabbit polyclonal anti-Protein DBF4 homolog A (10-59 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DBF4 |
| Gene ID | 10926 |
| Uniprot ID | DBF4A_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DBF4 at the amino acid range 10-59 |
| Immunogen Region | 10-59 aa |
| Specificity | Dbf4 Polyclonal Antibody detects endogenous levels of Dbf4 protein. |
Additional Info
| Post Translational Modifications | Phosphorylation increases its interaction with PSIP1. |
| Function | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. |
| Protein Name | Protein Dbf4 Homolog AActivator Of S Phase KinaseChiffon Homolog ADbf4-Type Zinc Finger-Containing Protein 1 |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-68962 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Dbf4 Homolog A antibodyAnti-Activator Of S Phase Kinase antibodyAnti-Chiffon Homolog A antibodyAnti-Dbf4-Type Zinc Finger-Containing Protein 1 antibodyAnti-DBF4 antibodyAnti-ASK antibodyAnti-DBF4A antibodyAnti-ZDBF1 antibody |
Information sourced from Uniprot.org